We went with our 1-year-old and 4-year-old last week and had a good time. Talk about the no-touching policy before you go; and if your kids are not big enough to follow that, strap them in a stroller (you can check one out at the front desk).
Warning: be sure to note which room as an adult-only exhibit so you can avoid it with your little ones.
Outside, they have a tactile exhibit that is lots of fun for young and old:
We call this one 'Spaghetti World'